Immunocytochemical staining with monoclonal antibodies in cytologically "negative" serous effusions from patients with malignant disease.
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چکیده
منابع مشابه
Immunocytochemical staining with monoclonal antibodies in cytologically "negative" serous effusions from patients with malignant disease.
In order to assess the practical value of immunocytochemical techniques in routine cytological diagnosis, a panel of three monoclonal antibodies (anti-CEA, Ca 1 and HMFG-2) were used to search for malignant cells in 53 samples of pleural or peritoneal fluid from 41 selected patients. All these patients suffered from malignant disease, but neoplastic cells had not been reported on conventional c...
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The Ca1 antibody was used in an alkaline phosphatase immunocytochemical method on cells obtained from 150 specimens of pleural and ascitic fluids. The results were compared with the routine cytology report based on the light microscopical appearances. The Ca1 antibody identified tumour cells in 51 of 57 specimens with malignant cells. The exceptions were four small cell carcinomas, one malignan...
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A panel of seven monoclonal antibodies was applied to smears of cell deposit from 70 pleural and peritoneal fluids, using an immunoalkaline phosphatase (IAP) procedure. The cases were chosen to show typical cytological patterns, both benign and malignant, and in this way the diagnostic value of the method could be assessed. The antibodies used were 2D1 (anti-leucocyte), Ca 1, HMFG-2 (anti-milk ...
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Cell smears from serous effusions containing large numbers of lymphoid cells were stained by the alkaline phosphatase-anti-alkaline phosphatase technique with a panel of monoclonal antibodies, including anti-B and anti-T cell antibodies and anti-HLA-DR. Samples from 17 patients with lymphoproliferative disorders--such as chronic lymphocytic leukaemia and non-Hodgkin's lymphoma--and from 19 pati...
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We read with interest the report by Assi and colleagues1 on the distribution of transudates and exudates between cytolog¬ ically proved malignant pleural effusions. The authors found that one of the 98 patients with malignant pleural effusions enrolled in the study, had a borderline transudate and had congestive heart failure at the time of the thoracentesis. The authors concluded that cytologi...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1983
ISSN: 0021-9746
DOI: 10.1136/jcp.36.10.1150